Guide To The Causes And Risk Factors For Stevens-Johnson Syndrome
Anticonvulsants
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Anticonvulsants are used to treat epilepsy and prevent seizures. However, suppose a patient experience blistering or other signs of Stevens-Johnson syndrome. In that case, their medication history should be looked into immediately. Not all prescriptions are implicated in the development of this syndrome. However, evidence indicates that anticonvulsants are a contributing factor for many patients.
Phenytoin was shown to present the highest risk of developing Stevens-Johnson syndrome in this class. Gabapentin and diazepam are also high-risk drugs for the development of this condition. Carbamazepine is another one. Researchers cannot conclusively state why these drugs cause Stevens-Johnson syndrome. However, they believe that the metabolites of the drugs, arene oxide, are responsible for these adverse reactions.
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